Skin Boosters · HA Or PN · Pacific Plaza
Profhilo vs Rejuran is not a contest between two brands but a choice between two jobs: Profhilo is hyaluronic acid that hydrates and firms thirsty, slackening skin, while the Rejuran skin booster is made of salmon-derived polynucleotides that support repair in damaged, reactive or textured skin. Neither is a filler. This guide is for anyone deciding between them, and it explains how Dr Sin Yong works out which your skin needs first.
Profhilo is 64 mg of hyaluronic acid in a 2 ml syringe, half in long chains and half in short ones, bonded by heat rather than chemically cross-linked. Hyaluronic acid is the skin's own water-binding molecule. Without cross-linking, the gel does not hold a shape; it spreads from a few injection points through the surrounding tissue, hydrating it and prompting fibroblasts to make more collagen and elastin.
Rejuran contains polynucleotides, purified fragments of DNA from salmon. They add little volume or water directly. Instead they act on repair pathways: they support fibroblast activity and help calm the inflammation that keeps damaged skin rough and reactive. Rejuran is placed as many fine deposits in the dermis rather than at a few points.
So one is a hydration-and-firmness treatment and the other a repair treatment. Neither lifts a cheek, fills a hollow or defines a jawline, and both are described further on the skin boosters page.
Side By Side
Both are offered at Atelier. The table shows what each does, not which is better.
| Profhilo | Rejuran | |
|---|---|---|
| What it is | 64 mg non-cross-linked hyaluronic acid per 2 ml, long and short chains bonded by heat | Polynucleotides purified from salmon DNA |
| Energy or mechanism | Hydrates as it spreads and prompts collagen and elastin | Repair signalling: supports fibroblasts and calms inflammation |
| Depth and target | Five points on each side of the face, spreading through the tissue | Many fine deposits in the dermis across the treated area |
| Typical sessions | Two sessions four weeks apart, then maintenance | Three to four sessions two to four weeks apart, then maintenance |
| Comfort and numbing | Numbed for comfort; a few injections | Topical anaesthetic first; many small injections |
| Downtime | Small bumps at the points, much softer by the evening | An even pattern of small bumps, typically settling in 24 to 48 hours |
| When results show | Hydration early; firmness builds over four to eight weeks | Gradually, across the course |
| Who it suits | Thin, dull, dehydrated skin that has lost its bounce | Post-acne texture, rough pores, sensitivity, redness, thin skin under the eyes |
| Precaution | Assessed individually | Fish or seafood allergy discussed first |
| At Atelier | Offered at Atelier | Offered at Atelier |
Which Skin
Profhilo fits thirsty, slackening skin: a face that has kept its shape but whose skin looks tired, dull and finely crinkled, often on the lower face and neck. Spread through the tissue, it gives a hydrated fullness at first and, over the following weeks, a modest gain in firmness. It is commonly considered from the late thirties onwards.
Rejuran fits skin that has been through something: texture left by acne, roughness around enlarged pores, sensitivity and redness, thin crepey skin under the eyes, or the wear of years of inflammation. It refines rather than plumps, and the change builds over the course rather than after one visit.
The overlap is narrower than advertising suggests. Profhilo will not settle reactive, damaged skin, and Rejuran will not restore bounce to skin that is mainly dehydrated and lax. If the real change is lost volume or descent, neither helps; that is a question for dermal fillers or lifting.
Using Both
Yes, but as a ranked decision rather than a default. Many faces show both thirst and damage, and the two treatments run as parallel courses, sequenced rather than stacked into one appointment. The assessment decides which problem to address first, usually the one that bothers you most and is most clearly present.
Combining means two full courses, each with its own maintenance, so it is planned with that in mind. Where looseness has gone beyond what better skin can hide, energy-based lifting is a separate step that no skin booster replaces.
How Atelier Decides
Dr SY looks at your skin under good light and under gentle stretch, separating dehydration and loss of bounce from texture, redness and scarring, and both from lost volume. He asks about your skincare, sensitivity, acne history and any fish or seafood allergy. The plan names one treatment, both in sequence, or something else entirely, and your quote follows it, as how we quote explains.
Treatment waits during pregnancy and breastfeeding and over active infection or inflamed skin. Afterwards, keep to the plain routine in Profhilo aftercare or Rejuran aftercare. Infection and allergic reactions are uncommon, but a lump that grows or hardens, or redness that spreads, should be seen rather than left to settle.
Atelier Aesthetics · Owned by AYA
9 Scotts Road, Pacific Plaza #12-01A, Singapore 228210 · +65 8023 7170
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