Dermal Pigment · Staged Laser · CityLink Mall

Hori's Naevus —
Grey Spots Beneath The Surface

Hori's naevus, also called ABNOM, is grey-blue speckling over both cheekbones, caused by pigment cells that sit deep in the dermis. This page explains how it is told apart from melasma, why creams leave it unchanged, and why Dr Sin Yong stages laser slowly, when it is chosen, because darkening after treatment is common.

The Mechanism

Pigment In The Wrong Layer

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In most brown marks, the pigment-making cells (melanocytes) sit at the base of the epidermis, the outer layer of skin. In Hori's naevus they lie lower, in the dermis. Hori described the condition in 1984, and its longer name, acquired bilateral naevus of Ota-like macules (ABNOM), says what it looks like: marks resembling naevus of Ota, on both sides, arriving in adult life.

Onset is usually in the twenties to forties, and most people affected are women with East or Southeast Asian heritage.

Cause One
Deep-Lying Cells
Spindle-shaped melanocytes are scattered through the upper and middle dermis.
Cause Two
Colour From Depth
The slate or blue-grey tone is attributed to the way light scatters off pigment lying deep in the skin.
Cause Three
A Late Switch
The cause is debated. One theory is that cells left behind during development are later activated by hormones, sun or inflammation.
Cause Four
Company On The Cheek
Melasma, sun spots and freckles often share the same cheeks, so the condition is easily misread.

Types

How It Differs From Melasma

Hori's naevus forms speckled, separate spots, placed evenly over both cheekbones and sometimes on the temples, forehead, sides of the nose and upper eyelids. Their tone stays grey or bluish, and a day in the sun does not make them noticeably darker. The whites of the eyes and the inside of the mouth are not involved. How it compares with other facial pigment is set out in pigmentation types.

Dr SY examines the cheeks in daylight, under a Wood's lamp and through a dermatoscope. Under the lamp, surface pigment stands out while dermal pigment barely changes. Through the dermatoscope, dermal pigment shows a diffuse blue-grey pattern; surface pigment, a brown network.

Specifications

Region
Both cheekbones; at times the temples, forehead, sides of the nose and upper eyelids
Assessment
Daylight, Wood's lamp and dermatoscopy, looking for coexisting melasma
Modalities
Sun protection and melasma control first, then staged picosecond laser for the dermal spots, or no laser
Review
Response checked before each visit; dermal pigment followed over a year or more
Type I
Hori's Naevus
Separate grey-blue or grey-brown speckles on both cheekbones, appearing in adult life and unmoved by cream.
Type II
Melasma
Soft-edged brown patches that merge across cheeks, forehead or upper lip, and shift with sun, heat and hormones.
Type III
Naevus Of Ota
Usually one blue-grey patch on one side of the face, often reaching the white of the eye.
Type IV
Freckles And Sun Spots
Brown surface marks: freckles that darken in the sun, and sharply bordered spots that gather over years.

The Decision

Diagnosis Before Any Laser

Lightening creams such as hydroquinone, azelaic acid, tranexamic acid, retinoids and vitamin C act on pigment made in the epidermis, or on how quickly surface cells shed. Hori's naevus lies below the basement membrane, beyond their reach, and is not carried off as skin renews. Facials and peels also act only at the surface, and the harsher ones can leave new brown marks.

The order of care. The diagnosis is confirmed first, and any melasma identified, because heat can darken it. Sun protection comes next and, where melasma is present, topical control. Only then does laser begin, conservatively and in stages, with the gap between visits set by how your skin responded rather than by a calendar. A small test area may come first where the reaction is hard to predict.

When to wait. Laser is put off after a recent tan or sunburn, while the cheeks are inflamed or infected, in pregnancy, and while you take medicines that make skin sensitive to light. If melasma on the same cheek is not yet under control, that comes first.

When to look further. A one-sided patch reaching the white of the eye suggests naevus of Ota, and an eye assessment comes before any laser. Any one spot that looks different, because it is new, irregular in outline or changing, is examined to rule out another cause. No laser at all is always one of the options.

Facial Pigmentation Types

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Lasers That Reach The Dermis

Dermal pigment needs a short-pulse laser that breaks pigment into fragments while little heat spreads around it. In the published literature, 1064 nm Nd:YAG, Q-switched nanosecond or picosecond, is the mainstay, because it passes through surface melanin with less absorption. Shorter 532 nm light is absorbed mainly near the surface, which makes it a tool for superficial marks rather than for Hori's naevus.

At Atelier, the dermal spots are treated with a picosecond laser on the DEKA TORO platform, in staged, conservative sessions. Melasma on the same cheek is managed first, on its own plan; see melasma.

Hori's naevus usually needs several sessions over a year or more, and the spots can look darker for a while after each one. Dr SY goes through this before the first session. Dr Sin Yong holds a Key Opinion Leader appointment with DEKA.

Safety

When The Skin Darkens

The main risk is post-inflammatory hyperpigmentation (PIH), new brown marks that follow inflammation. It is common with this condition, and the risk is higher with higher energies, with sessions repeated too soon, with sun on freshly treated skin, and in Fitzpatrick III to V skin. It generally fades, helped by time and strict sun protection; see post-inflammatory hyperpigmentation.

Laser over unrecognised melasma can make it flare; a published report describes melasma appearing after 1064 nm treatment of ABNOM. Less common problems include pale spots, redness that lingers, blisters or crusts, and a smaller improvement than expected.

In the weeks after a session, contact the clinic if you see blistering or thick crusting, if pain is getting worse, or if the skin darkens markedly. For problems after laser elsewhere, see complication care.

FAQ

Hori's Naevus — Common Questions

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Possibly that the pigment is too deep for a cream to reach. Grey or bluish spots that stay separate over both cheekbones are typical of Hori's naevus, which sits in the dermis, below where lightening creams act. Some people have both conditions, so a cream may have helped the melasma and left the deeper spots behind. An examination under a Wood's lamp and dermatoscope sorts out which is which.
Usually the melasma. In Singapore it is common to have both on the same cheeks. Melasma responds to sun protection, trigger control and topical treatment, and heat can darken it, so it is settled before any laser goes near the deeper spots. The Hori's component then needs a laser that reaches the dermis, and the plan is ordered so that treating it does not provoke the melasma. Both are mapped at the first visit.
A picosecond laser on the DEKA TORO platform. In the published literature, picosecond lasers, including 1064 nm picosecond devices, are among those used for this condition. The name of the device matters less than the settings, how far apart the sessions are and whether melasma has been controlled first. Because darkening after treatment is common with Hori's naevus, the plan stays conservative.
Published case series describe little recurrence once the dermal pigment has cleared. That is not a promise for any one person, and getting there usually takes a year or more of staged treatment. Sun spots or melasma can still appear later on the same cheeks, because those are surface conditions, so daily sun protection stays part of your routine.
No. Hori's naevus is benign. It is not linked to skin cancer or to any internal disease, and it does not involve the eye. Whether to treat it is your choice, and leaving it alone is reasonable. The exception is one spot that does not match the rest: a mark that is new, irregular in outline or colour, or changing should be examined, because it may have a different cause.

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References

  1. Ministry of Health, Singapore
  2. HealthHub, Singapore — public health information
  3. Dermatologic Therapy (2020) — systematic review of treatment options for Hori's naevus
  4. Journal of the American Academy of Dermatology (2009) — Hori naevus (ABNOM): causes and treatment considerations
  5. The Journal of Dermatology (2016) — melasma induced by 1064 nm Q-switched Nd:YAG laser treatment of ABNOM
  6. DermNet — Melasma (facial pigmentation)

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